A bedside urine test for human choriogonadotropin (hCG) as sensitive as serum radioimmunoassays.
نویسندگان
چکیده
منابع مشابه
Four rapid serum-urine combination assays of choriogonadotropin (hCG) compared and assessed for their utility in quantitative determinations of hCG.
We evaluated the performance of four visually read pregnancy tests (TestPack Plus hCG Combo, ICON II hCG, SureCell hCG-Serum/Urine and PregnaGen 1-Step) designed to detect increased concentrations of choriogonadotropin (hCG) in either serum or urine samples. The biochemical sensitivities and specificity in both serum and urine samples were similar for each kit. All kits correctly identified pre...
متن کاملMeasurement of the free alpha subunit of human glycoprotein hormones by a monoclonal antibody-based immunoradiometric assay, and further exploration of antigenic sites on the choriogonadotropin molecule.
Three monoclonal antibodies were raised against the free alpha subunit of choriogonadotropin (hCG); each recognized a different antigenic site on the molecule. One (antibody 42) preferentially bound to the alpha subunit when it was coupled to the beta subunit as dimeric choriogonadotropin (hCG), thyrotropin (TSH), lutropin (LH), or follitropin (FSH). Antibody 71 showed some cross-reaction with ...
متن کاملUrine of Patients with Malignant Pancreatic and Biliary Fragment of Human Choriogonadotropin in the Serum
Human Choriogonadotropin (hCG), its free /} subunit (£fh( '(>), and the core ,(h( (. fragment (c/3hCG) were measured by highly sensitive timeresolved immunofluorometric assays in the serum and urine of 29 pa tients with pancreatic cancer, 7 patients with biliary cancer, and 45 patients with benign pancreatic or biliary diseases. The results were compared with those of an ageand sex-matched ref...
متن کاملA specific and sensitive radioimmunoassay for human choriogonadotropin.
A specific and sensitive radioimmunoassay for human choriogonadotropin (hCG) has been developed using rabbit antiserum to chemical analogs of beta subunit of human chorionic gonadotropin prepared by controlled reduction and S-alkylation of its disulfide linkages. The assay was highly specific for hCG as the binding of [125I]-hCG to the antibody was not affected by standard human lutropin, by hu...
متن کاملThe stratus automated immunofluorometric assay system: a modification for measuring urinary human choriogonadotropin.
The fluorometric enzyme immunoassays that can be run on the automated Stratus analyzer (American Dade, Miami, FL) are based on monoclonal antibodies coated to glass-fiber paper tabs. The available assays are specifically designed for quantification of analytes in plasma and serum, but not in urine. For example, eight urine samples with hCG concentrations <2.5 mt.units/L according to the Tandem-...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Clinical chemistry
دوره 32 8 شماره
صفحات -
تاریخ انتشار 1986